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Western blot analysis in U251 cell line lysates (35ug/lane).
BMPR1B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in U251 cell line lysates (35ug/lane).

BMPR1B Antibody

CATALOG NUMBER: 56-190

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human BMPR1B.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BMPR1B
Additional Names:
Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, CDw293, BMPR1B
Protein Accession Number:
O00238
Ncbi Gene Id Number:
658
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the bone morphogeneticprotein (BMP) receptor family of transmembrane serine/threoninekinases. The ligands of this receptor are BMPs, which are membersof the TGF-beta superfamily. BMPs are involved in endochondral boneformation and embryogenesis. These proteins transduce their signalsthrough the formation of heteromeric complexes of 2 different typesof serine (threonine) kinase receptors: type I receptors of about50-55 kD and type II receptors of about 70-80 kD. Type II receptorsbind ligands in the absence of type I receptors, but they requiretheir respective type I receptors for signaling, whereas type Ireceptors require their respective type II receptors for ligandbinding. Mutations in this gene have been associated with primarypulmonary hypertension.
Background Reference 1:
Mick, E., et al.Am Acad Child Adolesc Psychiatry 49(9):898-905(2010)
Background Reference 2:
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Background Reference 3:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 4:
Ma, Y., et al. J. Exp. Clin. Cancer Res. 29, 85 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-190

List Size:
400 ul

List Price:

$495.00

Datasheet
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