BRD2 Antibody

CATALOG NUMBER: 63-365

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This BRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human BRD2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
88 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BRD2
Additional Names:
Bromodomain-containing protein 2, O2711, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3
Protein Accession Number:
P25440
Protein Gi Number:
12230989
Ncbi Gene Id Number:
6046
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human protein may be part of a signal transduction pathway involved in growth control.
Background Reference 1:
Pal, D.K., et al., Am. J. Hum. Genet. 73(2):261-270 (2003).
Background Reference 2:
Crowley, T.E., et al., Mol. Endocrinol. 16(8):1727-1737 (2002).
Background Reference 3:
Denis, G.V., et al., Cell Growth Differ. 11(8):417-424 (2000).
Background Reference 4:
Taniguchi, Y., et al., Genomics 51(1):114-123 (1998).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-365

List Size:
400 ul

List Price:

$495.00

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