c kit (Ab 936) Antibody

CATALOG NUMBER: 79-430

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
c-kit (Ab-936) antibody was raised against a peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
This antibody detects endogenous level of total c-Kit protein.
Predicted Molecular Weight:
145 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
KIT
Additional Names:
PBT, SCFR, C-Kit, CD117, HSP27, HSP28, KIT, PBT
Protein Accession Number:
NP_000213.1
Protein Gi Number:
4557695
Ncbi Gene Id Number:
3815
Background:
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
Background Reference 1:
Martin, F. H. et al. (1990) Cell 63, 203-11. Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62. Gommerman, J. L. et al. (1997) J Biol Chem 272, 30519-25. Nocka, K. et al. (1990) EMBO J 9, 1805-13.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-430

List Size:
0.1 mg

List Price:

$370.00

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