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Western blot analysis of lysate from Daudi cell line, using C-rel (NFkB)-G601 Antibody at 1:1000 at each lane.
Western blot analysis of anti-C-rel (NFkB) Pab (AP6336c)in Jurkat (left) and mouse kidney (right) cell line lysate.
Western blot analysis of lysate from Daudi cell line, using C-rel (NFkB)-G601 Antibody at 1:1000 at each lane.

C-rel Antibody

CATALOG NUMBER: 62-252

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This C-rel (NFkB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-619 amino acids from the C-terminal region of human C-rel (NFkB).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
69 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
REL
Additional Names:
Proto-oncogene c-Rel, REL
Protein Accession Number:
Q04864
Protein Gi Number:
548720
Ncbi Gene Id Number:
5966
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB regulates the expression of a wide variety of genes that involved in apoptosis, viral life cycle, tumorigenesis, autoimmune diseases and inflammation. NF-kB is a heterodimer of members of the rel family of proteins such as p50, p65, and c-rel. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation precipitates degradation of IkB and modification of NF-kB/Rel proteins, permitting translocation of NF-kB/Rel (c-Rel and RelA) to the nucleus for action on target genes. The important role of c-Rel in B-cell development, growth, and survival has been intensively studied, as well as its function in differentiation and lymphopoiesis (particularly lymphoid cancer).
Background Reference 1:
Jain, A., et al., J. Clin. Invest. 114(11):1593-1602 (2004).
Background Reference 2:
Xiao, Q., et al., Appl. Immunohistochem. Mol. Morphol. 12(3):211-215 (2004).
Background Reference 3:
Houldsworth, J., et al., Blood 103(5):1862-1868 (2004).
Background Reference 4:
Phelps, C.B., et al., Oncogene 23(6):1229-1238 (2004).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-252

List Size:
400 ul

List Price:

$495.00

Datasheet
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