Flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in K562 cell line lysates (15ug/lane).

CACNA2D4 Antibody

CATALOG NUMBER: 62-014

Clonality:

Polyclonal

Tested Applications:

Flow, WB

Host Species:

Rabbit

Species Reactivity:

Human

Conjugate:

Unconjugated

Specifications

Host Species:

Rabbit

Species Reactivity:

Human

Immunogen:

This CACNA2D4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CACNA2D4.

Conjugate:

Unconjugated

Tested Applications:

Flow, WB

Application Note:

For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50

Predicted Molecular Weight:

128 kDa

Advanced Validation

Properties

Purification:

This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality:

Polyclonal

Isotype:

Rabbit Ig

Physical State:

Liquid

Buffer:

Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration:

batch dependent

Storage Conditions:

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

Ncbi Official Symbol:

CACNA2D4

Additional Names:

Voltage-dependent calcium channel subunit alpha-2/delta-4, Voltage-gated calcium channel subunit alpha-2/delta-4, Voltage-dependent calcium channel subunit alpha-2-4, Voltage-dependent calcium channel subunit delta-4, CACNA2D4

Protein Accession Number:

Q7Z3S7

Protein Gi Number:

296434419

Ncbi Gene Id Number:

93589

User Note:

Optimal dilutions for each application to be determined by the researcher.

Background

Background:

CACNA2D4 is a member of the alpha-2/delta subunitfamily, a protein in the voltage-dependent calcium channel complex.Calcium channels mediate the influx of calcium ions into the cellupon membrane polarization and consist of a complex of alpha-1,alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Variousversions of each of these subunits exist, either expressed fromsimilar genes or the result of alternative splicing. Research on ahighly similar protein in rabbit suggests the protein described inthis record is cleaved into alpha-2 and delta subunits. Alternatetranscriptional splice variants of this gene have been observed buthave not been thoroughly characterized.

Background Reference 1:

Wycisk, K.A., et al. Am. J. Hum. Genet. 79(5):973-977(2006)

Background Reference 2:

Qin, N., et al. Mol. Pharmacol. 62(3):485-496(2002)

Citations

Set Contents

Disclaimer

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-014

List Size:

400 ul

List Price:

$495.00

Datasheet

Shipping Info

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CACNA2D4 Antibody

Clonality:

Tested Applications:

Host Species:

Species Reactivity:

Conjugate:

Host Species:

Species Reactivity:

Immunogen:

Conjugate:

Tested Applications:

Application Note:

Predicted Molecular Weight:

Purification:

Clonality:

Isotype:

Physical State:

Buffer:

Concentration:

Storage Conditions:

Ncbi Official Symbol:

Additional Names:

Protein Accession Number:

Protein Gi Number:

Ncbi Gene Id Number:

User Note:

Background:

Background Reference 1:

Background Reference 2:

Disclaimer:

List Size:

Shipping Info

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