CACNB2 Antibody

CATALOG NUMBER: 58-054

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Immunogen:
This CACNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the Central region of human CACNB2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
74 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CACNB2
Additional Names:
Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, CACNB2, CACNLB2, MYSB
Protein Accession Number:
Q08289
Protein Gi Number:
145559447
Ncbi Gene Id Number:
783
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a subunit of a voltage-dependent calciumchannel protein which is a member of the voltage-gated calciumchannel superfamily. The gene product was originally identified asan antigen target in Lambert-Eaton myasthenic syndrome which is anautoimmune disorder. Mutations in this gene are associated withBrugada symdrome. Alternatively spliced variants have beenidentified for this gene.
Background Reference 1:
Burashnikov, E., et al. Heart Rhythm (2010) In press :
Background Reference 2:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 3:
Takeuchi, F., et al. Circulation 121(21):2302-2309(2010)
Background Reference 4:
Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-054

List Size:
400 ul

List Price:

$495.00

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