Cardiotrophin-1 Recombinant Protein

CATALOG NUMBER: 40-441

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEEYVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA AALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVETVLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LYGEWVSRTE GDLGQLVPGG VA
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of TF - 1 cells was < 1.0 ng/mL, corresponding to a specific activity of > 1 x 106 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Cardiotrophin-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Cardiotrophin-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Cardiotrophin-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Ctf1
Additional Names:
CT-1, Cardiotrophin-1, CT-1
Protein Accession Number:
NP_031821.1
Protein Gi Number:
6681075
Ncbi Gene Id Number:
13019
Background:
CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-441

List Size:
0.002 mg, 0.01 mg

List Price:

Price range: $199.00 through $305.00

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