CATSPER2 Antibody

CATALOG NUMBER: 60-254

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CATSPER2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human CATSPER2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
62 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CATSPER2
Additional Names:
Cation channel sperm-associated protein 2, CatSper2, CATSPER2
Protein Accession Number:
Q96P56
Protein Gi Number:
156631018
Ncbi Gene Id Number:
117155
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Calcium ions play a primary role in the regulation ofsperm motility. This gene belongs to a family of putative cationchannels that are specific to spermatozoa and localize to theflagellum. The protein family features a single repeat with sixmembrane-spanning segments and a predicted calcium-selective poreregion. This gene is part of a tandem repeat on chromosome 15q15;the second copy of this gene is thought to be a pseudogene.Additional splice variants have been described but theirfull-length nature has not been determined.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 3:
Zhang, D., et al. J. Biol. Chem. 281(31):22332-22341(2006)
Background Reference 4:
Clapham, D.E., et al. Pharmacol. Rev. 57(4):451-454(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-254

List Size:
400 ul

List Price:

$495.00

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