Caveolin 2 (phospho Tyr27) Antibody

CATALOG NUMBER: 79-888

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Caveolin 2 (phospho Tyr27) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y (p)-A-D) derived from Human Caveolin 2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of Caveolin 2 only when phosphorylated at tyrosine 27.
Predicted Molecular Weight:
26 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CAV2
Additional Names:
CAV2, Caveolin-2
Protein Accession Number:
NP_001224.1
Protein Gi Number:
4557413
Ncbi Gene Id Number:
858
Background:
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.
Background Reference 1:
Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996).
Background Reference 2:
Scherer P.E., J. Biol. Chem. 272:29337-29346(1997).
Background Reference 3:
Engelman J.A., FEBS Lett. 448:221-230(1999).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-888

List Size:
0.1 mg

List Price:

$376.00

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