CB1 Antibody

CATALOG NUMBER: 60-631

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human CB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CNR1
Additional Names:
Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR
Protein Accession Number:
P21554
Protein Gi Number:
115562
Ncbi Gene Id Number:
1268
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes one of two cannabinoid receptors. Thecannabinoids, principally delta-9-tetrahydrocannabinol andsynthetic analogs, are psychoactive ingredients of marijuana. Thecannabinoid receptors are members of the guanine-nucleotide-bindingprotein (G-protein) coupled receptor family, which inhibitadenylate cyclase activity in a dose-dependent, stereoselective andpertussis toxin-sensitive manner. The two receptors have been foundto be involved in the cannabinoid-induced CNS effects (includingalterations in mood and cognition) experienced by users ofmarijuana. Multiple transcript variants encoding two differentprotein isoforms have been described for this gene. [provided byRefSeq].
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Van Laere, K., et al. J. Nucl. Med. 51(9):1413-1417(2010)
Background Reference 3:
Larrinaga, G., et al. Histol. Histopathol. 25(9):1133-1138(2010)
Background Reference 4:
Monteleone, P., et al.Clin Psychopharmacol 30(4):441-445(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-631

List Size:
400 ul

List Price:

$495.00

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