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Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Antibody used in WB on Hum. Fetal Heart at 1 ug/ml.
Antibody used in WB on Hum. Fetal Liver at 1 ug/ml.
Antibody used in WB on Hum. Adult Placenta at 1 ug/ml.
Antibody used in WB on Human Heart at 0.2-1 ug/ml.

CBX2 Antibody

CATALOG NUMBER: 30-735

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
CBX2 antibody can be used for detection of CBX2 by ELISA at 1:1562500. CBX2 antibody can be used for detection of CBX2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1301 - Human Heart Tissue Lysate
Predicted Molecular Weight:
56 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store CBX2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
CBX2
Additional Names:
CBX2, CDCA6, M33, MGC10561, SRXY5
Protein Accession Number:
NP_005180
Protein Gi Number:
61743963
Ncbi Gene Id Number:
84733
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Background Reference 1:
Garcia, E., (1999) EMBO J. 18 (12), 3404-3418.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-735

List Size:
100 ul

List Price:

$519.00

Datasheet
Shipping Info

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