CC2D1A Antibody

CATALOG NUMBER: 58-358

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CC2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CC2D1A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
104 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CC2D1A
Additional Names:
Coiled-coil and C2 domain-containing protein 1A, Akt kinase-interacting protein 1, Five prime repressor element under dual repression-binding protein 1, FRE under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N, CC2D1A, AKI1
Protein Accession Number:
Q6P1N0
Protein Gi Number:
74737148
Ncbi Gene Id Number:
54862
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CC2D1A is a transcriptional repressor that bindsto a conserved 14-bp 5'-repressor element and regulates expressionof the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronalcells. The DNA binding and transcriptional repressor activities ofthe protein are inhibited by calcium. A mutation in this generesults in nonsyndromic mental retardation-3.
Background Reference 1:
Zhao, M., et al. J. Biol. Chem. 285(32):24372-24380(2010)
Background Reference 2:
Nakamura, A., et al. Biochem. Biophys. Res. Commun. 393(4):872-876(2010)
Background Reference 3:
Nakamura, A., et al. J. Cell Biol. 187(5):607-614(2009)
Background Reference 4:
McKay, G.J., et al. Invest. Ophthalmol. Vis. Sci. 50(2):533-539(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-358

List Size:
400 ul

List Price:

$495.00

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