CCDC50 Antibody

CATALOG NUMBER: 30-864

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCDC50.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
CCDC50 antibody can be used for detection of CCDC50 by ELISA at 1:1562500. CCDC50 antibody can be used for detection of CCDC50 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
721_B Cell Lysate
Predicted Molecular Weight:
56 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store CCDC50 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
CCDC50
Additional Names:
CCDC50, C3orf6, DFNA44, YMER
Protein Accession Number:
NP_848018
Protein Gi Number:
41281911
Ncbi Gene Id Number:
152137
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.
Background Reference 1:
Bohgaki, M., (2008) Biochim. Biophys. Acta 1783 (5), 826-837.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-864

List Size:
100 ul

List Price:

$519.00

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