CCDC50 Antibody

CATALOG NUMBER: 57-583

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CCDC50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human CCDC50.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
36 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCDC50
Additional Names:
Coiled-coil domain-containing protein 50, Protein Ymer, CCDC50, C3orf6
Protein Accession Number:
Q8IVM0
Protein Gi Number:
73619722
Ncbi Gene Id Number:
152137
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a soluble, cytoplasmic,tyrosine-phosphorylated protein with multiple ubiquitin-interactingdomains. Mutations in this gene cause nonsyndromic, postlingual,progressive sensorineural DFNA44 hearing loss. In mouse, theprotein is expressed in the inner ear during development andpostnatal maturation and associates with microtubule-basedstructures. This protein may also function as a negative regulatorof NF-kB signaling and as an effector of epidermal growth factor(EGF)-mediated cell signaling. Alternative splicing results inmultiple transcript variants encoding distinct isoforms. [providedby RefSeq].
Background Reference 1:
Farfsing, A., et al. Leukemia 23(11):2018-2026(2009)
Background Reference 2:
Kameda, H., et al. Biochem. Biophys. Res. Commun. 378(4):744-749(2009)
Background Reference 3:
Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
Background Reference 4:
Modamio-Hoybjor, S., et al. Am. J. Hum. Genet. 80(6):1076-1089(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-583

List Size:
400 ul

List Price:

$495.00

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