CCDC6 Antibody

CATALOG NUMBER: 60-534

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CCDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human CCDC6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCDC6
Additional Names:
Coiled-coil domain-containing protein 6, Papillary thyroid carcinoma-encoded protein, Protein H4, CCDC6, D10S170, TST1
Protein Accession Number:
Q16204
Protein Gi Number:
292494979
Ncbi Gene Id Number:
8030
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a coiled-coil domain-containing protein.The encoded protein is ubiquitously expressed and may function as atumor suppressor. A chromosomal rearrangement resulting in theexpression of a fusion gene containing a portion of this gene andthe intracellular kinase-encoding domain of the ret proto-oncogeneis the cause of thyroid papillary carcinoma.
Background Reference 1:
Leone, V., et al. Oncogene 29(30):4341-4351(2010)
Background Reference 2:
Richardson, D.S., et al. Cancer Res. 69(11):4861-4869(2009)
Background Reference 3:
Jazdzewski, K., et al. Proc. Natl. Acad. Sci. U.S.A. 105(20):7269-7274(2008)
Background Reference 4:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-534

List Size:
400 ul

List Price:

$495.00

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