CCKAR Antibody

CATALOG NUMBER: 60-512

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human CCKAR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCKAR
Additional Names:
Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R, CCKAR, CCKRA
Protein Accession Number:
P32238
Protein Gi Number:
416772
Ncbi Gene Id Number:
886
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a G-protein coupled receptor that bindsnon-sulfated members of the cholecystokinin (CCK) family of peptidehormones. This receptor is a major physiologic mediator ofpancreatic enzyme secretion and smooth muscle contraction of thegallbladder and stomach. In the central and peripheral nervoussystem this receptor regulates satiety and the release ofbeta-endorphin and dopamine.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Cong, P., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G742-G750 (2010) :
Background Reference 3:
Tiwari, A.K., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry (2010) In press :
Background Reference 4:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-512

List Size:
400 ul

List Price:

$495.00

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