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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

CCNDBP1 Antibody

CATALOG NUMBER: 60-533

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This CCNDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human CCNDBP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
40 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCNDBP1
Additional Names:
Cyclin-D1-binding protein 1, Grap2 and cyclin-D-interacting protein, Human homolog of Maid, CCNDBP1, DIP1, GCIP, HHM
Protein Accession Number:
O95273
Ncbi Gene Id Number:
23582
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene was identified by the interaction of its geneproduct with Grap2, a leukocyte-specific adaptor protein importantfor immune cell signaling. The protein encoded by this gene wasshown to interact with cyclin D. Transfection of this gene in cellswas reported to reduce the phosphorylation of Rb gene product bycyclin D-dependent protein kinase, and inhibit E2F1-mediatedtranscription activity. This protein was also found to interactwith helix-loop-helix protein E12 and is thought to be a negativeregulator of liver-specific gene expression. Several alternativelyspliced variants have been found for this gene. [provided byRefSeq].
Background Reference 1:
Lee, I., et al. Cancer Res. 70(11):4357-4365(2010)
Background Reference 2:
Seto, A., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 65 (PT 1), 21-24 (2009) :
Background Reference 3:
Ikushima, H., et al. EMBO J. 27(22):2955-2965(2008)
Background Reference 4:
Chen, W.C., et al. Histopathology 53(5):554-560(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-533

List Size:
400 ul

List Price:

$495.00

Datasheet
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