CCR4 Antibody

CATALOG NUMBER: 59-665

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human CCR4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCR4
Additional Names:
C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5, CD194, CCR4, CMKBR4
Protein Accession Number:
P51679
Protein Gi Number:
1705894
Ncbi Gene Id Number:
1233
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to theG-protein-coupled receptor family . It is a receptor for the CCchemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a groupof small polypeptide, structurally related molecules that regulatecell trafficking of various types of leukocytes. The chemokinesalso play fundamental roles in the development, homeostasis, andfunction of the immune system, and they have effects on cells ofthe central nervous system as well as on endothelial cells involvedin angiogenesis or angiostasis.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 3:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Background Reference 4:
Klapa, S., et al. Clin. Exp. Rheumatol. 28 (1 SUPPL 57), 72-80 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-665

List Size:
400 ul

List Price:

$495.00

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