CCR5 (CD195) Antibody

CATALOG NUMBER: 79-765

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
CCR5 (CD195) antibody was raised against a peptide sequence around aa.11~15 (D-I-N-Y-Y) derived from Human CCR5 (CD195).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total CCR5(CD195) protein.
Predicted Molecular Weight:
41 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CCR5
Additional Names:
CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, CREB2, CREBP1, CKR5
Protein Accession Number:
NP_000570.1
Protein Gi Number:
4502639
Ncbi Gene Id Number:
1234
Background:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Background Reference 1:
Samson M., Labbe O., Mollereau C., Vassart G., Parmentier M. Biochemistry 35:3362-3367 (1996) Raport C. J., Gosling J., Schweichart V. L., Gray P. W., Charo I. F. J. Biol. Chem. 271:17161-17166 (1996) Combadiere C., Ahuja S. K., Tiffany H. L., Murphy P. M. J. Leukoc. Biol. 60:147-152 (1996)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-765

List Size:
0.1 mg

List Price:

$370.00

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