CCR9 Antibody

CATALOG NUMBER: 57-310

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CCR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the C-terminal region of human CCR9.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCR9
Additional Names:
C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CDw199, CCR9, GPR28
Protein Accession Number:
P51686
Protein Gi Number:
114152781
Ncbi Gene Id Number:
10803
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the betachemokine receptor family. It is predicted to be a seventransmembrane protein similar to G protein-coupled receptors.Chemokines and their receptors are key regulators of the thymocytesmigration and maturation in normal and inflammation conditions. Thespecific ligand of this receptor is CCL25. It has been found thatthis gene is differentially expressed by T lymphocytes of smallintestine and colon, suggested a role in the thymocytes recruitmentand development that may permit functional specialization of immuneresponses in different segment of the gastrointestinal tract. Thisgene is mapped to the chemokine receptor gene cluster region. Twoalternatively spliced transcript variants have been described.
Background Reference 1:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 2:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Background Reference 3:
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Background Reference 4:
Segat, L., et al. Vaccine 28(10):2201-2206(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-310

List Size:
400 ul

List Price:

$495.00

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