CCRL2 Antibody

CATALOG NUMBER: 58-542

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CCRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human CCRL2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
40 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CCRL2
Additional Names:
C-C chemokine receptor-like 2, Chemokine receptor CCR11, Chemokine receptor X, Putative MCP-1 chemokine receptor, CCRL2, CCR11, CCR6, CKRX, CRAM, HCR
Protein Accession Number:
O00421
Ncbi Gene Id Number:
9034
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a chemokine receptor like protein, whichis predicted to be a seven transmembrane protein and most closelyrelated to CCR1. Chemokines and their receptors mediated signaltransduction are critical for the recruitment of effector immunecells to the site of inflammation. This gene is expressed at highlevels in primary neutrophils and primary monocytes, and is furtherupregulated on neutrophil activation and during monocyte tomacrophage differentiation. The function of this gene is unknown.This gene is mapped to the region where the chemokine receptor genecluster is located.
Background Reference 1:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 2:
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Background Reference 3:
Leick, M., et al. Immunology 129(4):536-546(2010)
Background Reference 4:
Segat, L., et al. Vaccine 28(10):2201-2206(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-542

List Size:
400 ul

List Price:

$495.00

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