CD1.1 Antibody [CB3]

CATALOG NUMBER: 99-333

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Chicken
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Chicken
Immunogen:
Lymphocytes from the bursa of Fabricius of outbred chickens
Conjugate:
Unconjugated
Tested Applications:
Flow
Application Note:
CD1.1 Antibody [CB3] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and immunoprecipitation assays.
Specificity:
CD1.1
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
CD1C
Ncbi Gene Id Number:
425801;425802
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8alpha+ cells. CD1.2 is expressed in TCRgammadelta cells but is nearly undetectable in TCRalphabeta. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-333

List Size:
0.5 mg

List Price:

$463.00

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