CD104 Antibody [346-11A]

CATALOG NUMBER: 99-002

Clonality:
Monoclonal
Tested Applications:
Flow, ICC, IHC-Fr, IHC-P, IP
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Immunogen:
Tumor-associated antigen TSP-180 purified from a transplantable BALB/c carcinoma
Conjugate:
Unconjugated
Tested Applications:
Flow, ICC, IHC-Fr, IHC-P, IP
Application Note:
CD104 Antibody [346-11A] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Specificity:
CD104
Clonality:
Monoclonal
Isotype:
IgG2a
physical-state:
Liquid
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
Itgb4
Additional Names:
Integrin beta4
Protein Accession Number:
A2A863
Ncbi Gene Id Number:
192897
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD104 represents the integrin beta4 subunit that associates non-covalently with integrin alpha6 (CD49f) to form the alpha6beta4 integrin heterodimer. The alpha6beta4 complex is expressed on the basal surface of a variety of epithelial cell types particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes. It also has been found to be associated with a number of malignant tissues. Hemidesmosomal alpha6beta4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments. It is not known if the monoclonal antibody 346-11A can block this adhesion.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-002

List Size:
0.5 mg

List Price:

$432.00

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