CD105 Antibody [MJ7/18] (PE)

CATALOG NUMBER: 76-828

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Eng
Additional Names:
Endo, CD105, AI528660, AI662476, S-endoglin, Eng
Ncbi Gene Id Number:
13805
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
Background Reference 1:
Ge, A. Z., Butcher, E. C. (1994). Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF--beta- ligand.Gene,138(1), 201-206.
Background Reference 2:
Onoe, T., Ohdan, H., Tokita, D., Shishida, M., Tanaka, Y., Hara, H., ... Asahara, T. (2005). Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice.The Journal of Immunology,175(1), 139-146.
Background Reference 3:
St-Jacques, S., Cymerman, U. R. S. Z. U. L. A., Pece, N. A. D. I. A., Letarte, M. (1994). Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells.Endocrinology,134(6), 2645-2657.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-828

List Size:
0.1 mg

List Price:

$391.00

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