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CD105 Antibody [MJ7/18] (PE)

CATALOG NUMBER: 76-829

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Eng
Additional Names:
Endo, CD105, AI528660, AI662476, S-endoglin, Eng
Ncbi Gene Id Number:
13805
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
Background Reference 1:
Mrquez, C., Trigueros, C., Franco, J. M., Ramiro, A. R., Carrasco, Y. R., Lpez-Botet, M., Toribio, M. L. (1998). Identification of a common developmental pathway for thymic natural killer cells and dendritic cells.Blood,91(8), 2760-2771.
Background Reference 2:
Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., ... Annunziato, F. (2008). Human interleukin 17producing cells originate from a CD161+ CD4+ T cell precursor.The Journal of experimental medicine,205(8), 1903-1916.
Background Reference 3:
Exley, M., Porcelli, S., Furman, M., Garcia, J., Balk, S. (1998). CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Valpha 24Jalpha Q T cell receptor alpha chains.The Journal of experimental medicine,188(5), 867-876.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-829

List Size:
0.2 mg

List Price:

$494.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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