CD105 Antibody [SN6] (PE)

CATALOG NUMBER: 76-873

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The SN6 monoclonal antibody specifically reacts with human CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells, activated macrophages, and a subset of bone marrow cells.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
ENG
Additional Names:
END, HHT1, ORW1, ENG
Ncbi Gene Id Number:
2022
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The SN6 monoclonal antibody specifically reacts with human CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells, activated macrophages, and a subset of bone marrow cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
Background Reference 1:
Murayama, T., Yokode, M., Kataoka, H., Imabayashi, T., Yoshida, H., Sano, H., ... Kita, T. (1999). Intraperitoneal administration of antic-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein Edeficient mice.Circulation,99(13), 1740-1746.
Background Reference 2:
Sudo, T., Nishikawa, S., Ogawa, M., Kataoka, H., Ohno, N., Izawa, A., Hayashi, S. (1995). Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M.Oncogene,11(12), 2469-2476.
Background Reference 3:
Yoshino, M., Yamazaki, H., Yoshida, H., Niida, S., Nishikawa, S. I., Ryoke, K., ... Hayashi, S. I. (2003). Reduction of osteoclasts in a critical embryonic period is essential for inhibition of mouse tooth eruption.Journal of Bone and Mineral Research,18(1), 108-116.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-873

List Size:
100 tests

List Price:

$419.00

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