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CD107a Antibody [H4A3] (PE)

CATALOG NUMBER: 76-891

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
LAMP1
Additional Names:
LAMPA, CD107a, LGP120, LAMP1
Ncbi Gene Id Number:
3916
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.
Background Reference 1:
Chen, J. W., Cha, Y. I. N. G., Yuksel, K. U., Gracy, R. W., August, J. T. (1988). Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.Journal of Biological Chemistry,263(18), 8754-8758.
Background Reference 2:
Grtzkau, A., Smorodchenko, A., Lippert, U., Kirchhof, L., Artuc, M., Henz, B. M. (2004). LAMP1 and LAMP2, but not LAMP3, are reliable markers for activationinduced secretion of human mast cells.Cytometry Part A,61(1), 62-68.
Background Reference 3:
Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J. J., Van den Brule, F., Castronovo, V., ... Coninck, W. D. (1998). Expression of Lamp1 and Lamp2 and their interactions with galectin3 in human tumor cells.International journal of cancer,75(1), 105-111.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-891

List Size:
100 tests

List Price:

$419.00

Out of stock

Datasheet
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