CD115 Antibody [AFS98] (APC)

CATALOG NUMBER: 76-882

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
APC
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
APC
Tested Applications:
Flow
Specificity:
The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Csf1r
Additional Names:
Fms, CD115, Csfmr, Fim-2, CSF-1R, M-CSFR, M-CSF-R, AI323359, Csf1r
Ncbi Gene Id Number:
12978
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Background Reference 1:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 2:
Wagner, B. J., Lindau, D., Ripper, D., Stierhof, Y. D., Glatzle, J., Witte, M., ... Knigsrainer, A. (2011). Phagocytosis of dying tumor cells by human peritoneal mesothelial cells.Journal of cell science,124(10), 1644-1654.
Background Reference 3:
Leca, G., Mansur, S. E., Bensussan, A. (1995). Expression of VCAM-1 (CD106) by a subset of TCR gamma delta-bearing lymphocyte clones. Involvement of a metalloprotease in the specific hydrolytic release of the soluble isoform.The Journal of Immunology,154(3), 1069-1077.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-882

List Size:
0.025 mg

List Price:

$217.00

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