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CD11a Antibody [HI111]

CATALOG NUMBER: 76-152

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
ITGAL
Additional Names:
CD11A, LFA-1, LFA1A, ITGAL
Ncbi Gene Id Number:
3683
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2).
Background Reference 1:
Inghirami, G., Wieczorek, R., Zhu, B. Y., Silber, R., Dalla-Favera, R., Knowles, D. M. (1988). Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia.Blood,72(4), 1431-1434.
Background Reference 2:
Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 3:
Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse-Anthony, C. P., ... Schleimer, R. P. (1991). Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules.The Journal of experimental medicine,173(6), 1553-1557.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-152

List Size:
0.05 mg

List Price:

$302.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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