CD11b Antibody [3A33]

CATALOG NUMBER: 98-638

Clonality:
Monoclonal
Tested Applications:
ELISA, Flow, IP, Multiplex, Neutralization Assay
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Immunogen:
Peritoneal macrophages from B6D2 hybrid mice
Conjugate:
Unconjugated
Tested Applications:
ELISA, Flow, IP, Multiplex, Neutralization Assay
Application Note:
CD11b Antibody [3A33] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
Specificity:
CD11b
Clonality:
Monoclonal
Isotype:
IgG2a
physical-state:
Liquid
Buffer:
Supplied in PBS
Concentration:
0.5 mg/mL
Storage Conditions:
Store vial at -20°C
Ncbi Official Symbol:
Itgam
Additional Names:
Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR
Protein Accession Number:
P05555
Ncbi Gene Id Number:
16409
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

98-638

List Size:
0.5 mg

List Price:

$463.00

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