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Human IL-7 R alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human IL-7 R alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CD127 Recombinant Protein

CATALOG NUMBER: 96-457

Tested Applications:
WB
Specifications
Source Species:
HEK293 cells
Species:
Human
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Glu 21 - Gly 236
Fusion Tag:
C-Fc Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
51 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized rhIL7Ra Fc Chimera at 0. 25μg/ml (100μl/well) on a Rabbit anti-human IgG Fc antibody, the concentration of rhIL-7 that produces 50% of the optimal binding response is found to be approximately 20 - 100 ng/mL.
Purity:
>95% as determined by SDS-PAGE.
Physical State:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
IL7R
Additional Names:
IL7Ra, CD127
Protein Accession Number:
P16871-1
Ncbi Gene Id Number:
3575
Background:
Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
Background Reference 1:
Noguchi M., et al., 1994, Science 262 (5141): 1877–80.
Background Reference 2:
Kroemer RT., et al., 1997, Protein Eng. 9 (12): 1135–42.
Background Reference 3:
McElroy C.A., et al., 2009, Structure 17:54-65.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-457

List Size:
0.1 mg

List Price:

$420.00

Out of stock

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