CD137 Antibody

CATALOG NUMBER: 36-216

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Human CD137.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
Flow Cytometry: (1:500-1:1,000). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 with 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Specificity:
Recognizes human CD137. Detects a band of ~29kDa by Western blot. Does not cross-react with mouse CD137.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
TNFRSF9
Additional Names:
4-1BB; TNFRSF9
Protein Accession Number:
728738
Protein Gi Number:
Q07011
Ncbi Gene Id Number:
3604
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-216

List Size:
100 ug

List Price:

$408.00

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