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CD137L Antibody [41B436]

CATALOG NUMBER: 36-030

Clonality:
Monoclonal
Tested Applications:
ELISA, Flow, ICC, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
Recombinant human CD137L extracellular domain.
Conjugate:
Unconjugated
Tested Applications:
ELISA, Flow, ICC, WB
Application Note:
ELISA: (direct or indirect: 1:500-1:5,000). Flow Cytometry: (1:1,000). Immunocytochemistry: (see reference Nr. 2). Western blot: (1:2,000). Optimal conditions should be determined individually for each application.
Specificity:
Recognizes extracellular domain of human CD137L. Does not cross-react with mouse CD137L.
Clonality:
Monoclonal
Isotype:
IgG1, kappa
physical-state:
Liquid
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
TNFSF9
Additional Names:
4-1BBL; TNFSF9
Protein Accession Number:
728739
Protein Gi Number:
P41273
Ncbi Gene Id Number:
8744
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-030

List Size:
100 ug

List Price:

$446.00

Datasheet
Shipping Info

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