CD14 Antibody [61D3]

CATALOG NUMBER: 76-385

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
CD14
Additional Names:
CD14, CD14
Ncbi Gene Id Number:
929
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS). It is expressed on some dendritic cells, monocytes, and neutrophils. CD14 is involved in the body’s innate immune response and cytokine expression in monocytes and neutrophils.
Background Reference 1:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 2:
Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
Background Reference 3:
Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells.Nature,392(6675), 505-509.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-385

List Size:
0.1 mg

List Price:

$436.00

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