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Mouse CD155, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Mouse TIGIT, His Tag at 10 ug/mL (100 uL/well) can bind Mouse CD155, Mouse IgG2a Fc Tag with a linear range of 0.039-1.25 ug/mL (QC tested).
Mouse CD155, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CD155 / PVR Recombinant Protein

CATALOG NUMBER: 11-539

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Asp 29 - Leu 348
Fusion Tag:
Mouse IgG Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 61.8 kDa. The protein migrates as 35 kDa and 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Predicted Molecular Weight:
61.8 kDa
Purity:
>95% as determined by reduced SDS-PAGE.
physical-state:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
Pvr
Additional Names:
PVR,FLJ25946,PVS,CD155,TAGE4,HVED,NECL5
Protein Accession Number:
NP_081790.1
Ncbi Gene Id Number:
52118
Background:
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
Background Reference 1:
Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47): 18284-18289.
Background Reference 2:
Maier MK., et al., 2007, European Journal of Immunology, 37 (8): 2214-2225.
Background Reference 3:
He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1): 79-84.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-539

List Size:
0.05 mg

List Price:

$577.00

Datasheet
Shipping Info

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