CD155 Recombinant Protein

CATALOG NUMBER: 96-841

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Trp 21 - Asn 343
Fusion Tag:
mouse IgG2a Fc tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Predicted Molecular Weight:
62.2 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human TIGIT, Fc Tag at 2 ug/mL (100 uL/well) can bind Human CD155, mouse IgG2a Fc tag with a linear range of 0.98-7.81 ng/mL.
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 0.1 EU per ug by the LAL method.
physical-state:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
CD155
Additional Names:
PVR,FLJ25946,PVS,CD155,TAGE4,HVED,NECL5
Protein Accession Number:
NP_006496.2
Ncbi Gene Id Number:
5817
Background:
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
Background Reference 1:
Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47): 18284-18289.
Background Reference 2:
Maier MK., et al., 2007, European Journal of Immunology, 37 (8): 2214-2225.
Background Reference 3:
He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1): 79-84.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-841

List Size:
0.1 mg

List Price:

$577.00

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