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CD16 Antibody [3G8] (FITC)

CATALOG NUMBER: 76-581

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
FITC
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
FCGR3A
Additional Names:
CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA, FCGR3A
Ncbi Gene Id Number:
2214
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Background Reference 1:
Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
Background Reference 2:
Hayakawa, Y., Huntington, N. D., Nutt, S. L., Smyth, M. J. (2006). Functional subsets of mouse natural killer cells.Immunological reviews,214(1), 47-55.
Background Reference 3:
Tittarelli, A., Mendoza-Naranjo, A., Faras, M., Guerrero, I., Ihara, F., Wennerberg, E., ... Salazar-Onfray, F. (2014). Gap Junction Intercellular Communications Regulate NK Cell Activation and Modulate NK Cytotoxic Capacity.The Journal of Immunology,192(3), 1313-1319.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-581

List Size:
25 tests

List Price:

$259.00

Out of stock

Datasheet
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