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CD197 Antibody [3D12] (PE)

CATALOG NUMBER: 76-932

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CCR7
Additional Names:
BLR2, EBI1, CCR-7, CD197, CDw197, CMKBR7, CC-CKR-7, CCR7
Ncbi Gene Id Number:
1236
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.
Background Reference 1:
Gattei, V., Godeas, C., Degan, M., Rossi, F. M., Aldinucci, D., Pinto, A. (1999). Characterization of antiCD138 monoclonal antibodies as tools for investigating the molecular polymorphism of syndecan1 in human lymphoma cells.British journal of haematology,104(1), 152-162.
Background Reference 2:
Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G., Bernfield, M. (2000). Shedding of syndecan-1 and-4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3sensitive metalloproteinase.The Journal of cell biology,148(4), 811-824.
Background Reference 3:
Itoua Maga, R., Lemieux, J., Roy, A., Simard, C., Nron, S. (2014). Flow Cytometry Assessment of In Vitro Generated CD138.BioMed research international,2014.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-932

List Size:
25 tests

List Price:

$249.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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