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CD1d Antibody [1B1]

CATALOG NUMBER: 76-085

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Rat IgG2b, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
Cd1d1
Additional Names:
Cd1a, Cd1d, CD1.1, Ly-38, AI747460, Cd1d1
Ncbi Gene Id Number:
12479
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules. CD1d is expressed by mouse leukocytes, epithelial cells, thymocytes, and dendritic cells and is the only molecules in the CD1 family to have been found in the mouse. The 1B1 antibody detects CD1d in association with the Beta2m molecule.
Background Reference 1:
Szalay, G., Ladel, C. H., Blum, C., Brossay, L., Kronenberg, M., Kaufmann, S. H. (1999). Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF--beta-2 and Th1 cytokines and ameliorates listeriosis in mice.The Journal of Immunology,162(12), 6955-6958.
Background Reference 2:
Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M., Bendelac, A. (1998). CD1. 1 expression by mouse antigen-presenting cells and marginal zone B cells.The Journal of Immunology,160(7), 3121-3127.
Background Reference 3:
Amano, M., Baumgarth, N., Dick, M. D., Brossay, L., Kronenberg, M., Herzenberg, L. A., Strober, S. (1998). CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: -beta-2-microglobulin-dependent and independent forms.The Journal of Immunology,161(4), 1710-1717.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-085

List Size:
0.1 mg

List Price:

$328.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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