CD20 Antibody [2H7] (APC)

CATALOG NUMBER: 76-008

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
APC
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
APC
Tested Applications:
Flow
Specificity:
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG2b, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
MS4A1
Additional Names:
B1, S7, Bp35, CD20, CVID5, MS4A2, LEU-16, MS4A1
Ncbi Gene Id Number:
931
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
Background Reference 1:
Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 2:
Polyak, M. J., Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes
Background Reference 3:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-008

List Size:
100 tests

List Price:

$467.00

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