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Human CD200, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%.
Human CD200, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%.

CD200 Recombinant Protein

CATALOG NUMBER: 96-573

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 31 - Gly 232
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
23.4 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD200R1 at 2μg/ml,the concentration of rhCD200 that produces 50% of the optimal binding response is appoximately 0. 5-16 ng/mL.
Purity:
>98% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
CD200
Additional Names:
CD200, MOX1, MOX2, MRC, OX-2, My033
Protein Accession Number:
AAH22522
Ncbi Gene Id Number:
4345
Background:
CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
Background Reference 1:
McCaughan, G.W. et al., 1987, Immunogenetics 25:329-335.
Background Reference 2:
Chen, Z. et al., 2006, Mol Immunol. 43 (6): 579-587.
Background Reference 3:
Wright GJ., et al., 2003, J. Immunol. 171 (6): 3034–46.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-573

List Size:
0.1 mg

List Price:

$463.00

Datasheet
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