CD200R1 Antibody

CATALOG NUMBER: 58-219

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This CD200R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human CD200R1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CD200R1
Additional Names:
Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, CD200R1, CD200R, CRTR2, MOX2R, OX2R
Protein Accession Number:
Q8TD46
Protein Gi Number:
26006823
Ncbi Gene Id Number:
131450
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a receptor for the OX-2 membraneglycoprotein. Both the receptor and substrate are cell surfaceglycoproteins containing two immunoglobulin-like domains. Thisreceptor is restricted to the surfaces of myeloid lineage cells andthe receptor-substrate interaction may function as a myeloiddownregulatory signal. Mouse studies of a related gene suggest thatthis interaction may control myeloid function in a tissue-specificmanner. Alternative splicing of this gene results in multipletranscript variants.
Background Reference 1:
Luo, X.G., et al. Neurochem. Res. 35(4):540-547(2010)
Background Reference 2:
Mihrshahi, R., et al. J. Immunol. 183(8):4879-4886(2009)
Background Reference 3:
Koning, N., et al. J. Neuropathol. Exp. Neurol. 68(2):159-167(2009)
Background Reference 4:
Meuth, S.G., et al. J. Neuroimmunol. 194 (1-2), 62-69 (2008) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-219

List Size:
400 ul

List Price:

$495.00

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