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CD21 Antibody [HB5] (FITC)

CATALOG NUMBER: 76-154

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
FITC
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
mouse IgG2a, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CR2
Additional Names:
CR, C3DR, CD21, CVID7, SLEB9, CR2
Ncbi Gene Id Number:
1380
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein. CD21 is reported to be involved in B cell activation and proliferation. It is expressed on follicular dendritic cells, mature B cells, a subset of T cells, and a subset of epithelial cells. It is the receptor utilized by the Epstein-Barr virus to infect B cells.
Background Reference 1:
Tedder, T. F., Clement, L. T., Cooper, M. D. (1984). Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody.The Journal of Immunology,133(2), 678-683.
Background Reference 2:
Fingeroth, J. D., Weis, J. J., Tedder, T. F., Strominger, J. L., Biro, P. A., Fearon, D. T. (1984). Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.Proceedings of the National Academy of Sciences,81(14), 4510-4514.
Background Reference 3:
Nemerow, G. R., Wolfert, R. O. B. E. R. T., McNaughton, M. E., Cooper, N. R. (1985). Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2).Journal of virology,55(2), 347-351.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-154

List Size:
100 tests

List Price:

$419.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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