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CD252 Antibody [RM134L] (APC)

CATALOG NUMBER: 76-944

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
APC
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
APC
Tested Applications:
Flow
Specificity:
The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2b, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Tnfsf4
Additional Names:
Ath1, gp34, Ath-1, Ox40l, TXGP1, CD134L, OX-40L, Txgp1l, Tnfsf4
Ncbi Gene Id Number:
22164
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
Background Reference 1:
Flo, T. H., Halaas, ., Lien, E., Ryan, L., Teti, G., Golenbock, D. T., ... Espevik, T. (2000). Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.The Journal of Immunology,164(4), 2064-2069.
Background Reference 2:
Lien, E., Sellati, T. J., Yoshimura, A., Flo, T. H., Rawadi, G., Finberg, R. W., ... Golenbock, D. T. (1999). Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.Journal of Biological Chemistry,274(47), 33419-33425.
Background Reference 3:
Cook, E. B., Stahl, J. L., Esnault, S., Barney, N. P., Graziano, F. M. (2005). Toll-like receptor 2 expression on human conjunctival epithelial cells: a pathway for

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-944

List Size:
0.025 mg

List Price:

$217.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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