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CD278 [ICOS] Recombinant Protein

CATALOG NUMBER: 90-446

Specifications
source-species:
CHO cells
Species:
Mouse
source-species:
CHO cells
Recombinant Protein Sequence:
The extracellular domain of mouse CD278 [ICOS] (aa 21-142) is fused to the N-terminus of the Fc region of mouse IgG2a.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Purity:
≥98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
physical-state:
Lyophilized
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Ncbi Official Symbol:
Icos
Additional Names:
ICOS, Inducible T Cell Costimulator, CRP1, CD28-related Protein-1, AILIM
Protein Accession Number:
NP_059508
Protein Gi Number:
224809335
Ncbi Gene Id Number:
54167
Background:
CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-446

List Size:
100 ug

List Price:

$515.00

Datasheet
Shipping Info

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