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CD282 Antibody [mT2.7] (FITC)

CATALOG NUMBER: 76-951

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
FITC
Specifications
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG2a, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Tlr2
Additional Names:
Ly105, Tlr2
Ncbi Gene Id Number:
24088
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on monocytes, macrophages, dendritic cells, and the RAW264.7 cell line and is involved distinguishing bacterial lipoproteins.
Background Reference 1:
Mechetner, E. B., Roninson, I. B. (1992). Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.Proceedings of the National Academy of Sciences,89(13), 5824-5828.
Background Reference 2:
Chaudhary, P. M., Mechetner, E. B., Roninson, I. B. (1992). Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments].Blood,80(11), 2735-2739.
Background Reference 3:
Goda, K., Fenyvesi, F., Bacs, Z., Nagy, H., Mrin, T., Megyeri, A., ... Szab, G. (2007). Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody.Journal of Pharmacology and Experimental Therapeutics,320(1), 81-88.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-951

List Size:
0.025 mg

List Price:

$259.00

Out of stock

Datasheet
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