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CD284 Antibody [UT41] (PE)

CATALOG NUMBER: 76-966

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Mouse
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The UT41 monoclonal antibody specifically reacts with mouse CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Tlr4
Additional Names:
Lps, Ly87, Ran/M1, Rasl2-8, Tlr4 , Tlr4
Ncbi Gene Id Number:
21898
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The UT41 monoclonal antibody specifically reacts with mouse CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The UT41 antibody can bind to TLR4 with or without the formation of the TLR4/MD-2 complex.
Background Reference 1:
Hutloff, A., Dittrich, A. M., Beier, K. C., Eljaschewitsch, B., Kraft, R., Anagnostopoulos, I., Kroczek, R. A. (1999). ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28.Nature,402, 21-24.
Background Reference 2:
Quiroga, M. F., Pasquinelli, V., Martnez, G. J., Jurado, J. O., Zorrilla, L. C., Musella, R. M., ... Garca, V. E. (2006). Inducible costimulator: a modulator of IFN- gammaproduction in human tuberculosis.The Journal of Immunology,176(10), 5965-5974.
Background Reference 3:
Buonfiglio, D., Bragardo, M., Redoglia, V., Vaschetto, R., Bottarel, F., Bonissoni, S., ... Dianzani, U. (2000). The T cell activation molecule H4 and the CD28like molecule ICOS are identical.European journal of immunology,30(12), 3463-3467.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-966

List Size:
0.025 mg

List Price:

$275.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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