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CD289 Antibody [M9.D6] (FITC)

CATALOG NUMBER: 76-979

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
FITC
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
FITC
Tested Applications:
Flow
Specificity:
The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Tlr9
Additional Names:
B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, Tlr9
Ncbi Gene Id Number:
81897
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Background Reference 1:
Walzer, T., Blry, M., Chaix, J., Fuseri, N., Chasson, L., Robbins, S. H., ... Vivier, E. (2007). Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.Proceedings of the National Academy of Sciences,104(9), 3384-3389.
Background Reference 2:
Joncker, N. T., Fernandez, N. C., Treiner, E., Vivier, E., Raulet, D. H. (2009). NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model.The Journal of Immunology,182(8), 4572-4580.
Background Reference 3:
Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., ... Mandelboim, O. (2006). Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1.Nature immunology,7(5), 517-523.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-979

List Size:
0.1 mg

List Price:

$519.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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