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Human peripheral blood lymphocytes were stained with PE-Cy7 SK7 with relevant isotype control in Red.
Human peripheral blood lymphocytes were stained with PE-Cy7 SK7 with relevant isotype control in Red.

CD3 Antibody [SK7] (PE-Cy7)

CATALOG NUMBER: 76-302

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE-Cy7
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
PE-Cy7
Tested Applications:
Flow
Specificity:
The SK7 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CD3E
Additional Names:
T3E, TCRE, IMD18, CD3E
Ncbi Gene Id Number:
916
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The SK7 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes.
Background Reference 1:
Van Dongen, J. J., Krissansen, G. W., Wolvers-Tettero, I. L., Comans-Bitter, W. M., Adriaansen, H. J., Hooijkaas, H., ... Terhorst, C. (1988). Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies.Blood,71(3), 603-612.
Background Reference 2:
Haynes, B. F. (1986). Summary of T cell studies performed during the second international workshop and conference on human leukocyte differentiation antigens. InLeukocyte typing II(pp. 3-30). Springer New York.
Background Reference 3:
Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57(12), 1159-1167.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-302

List Size:
25 tests

List Price:

$302.00

Datasheet
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