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Human CD3E&CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag(MALS verified) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human CD3E&CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag(MALS verified) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CD3 epsilon&CD3 gamma Heterodimer Recombinant Protein

CATALOG NUMBER: 11-551

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)
Fusion Tag:
His Tag & Fc Tag & Flag Tag
Tested Applications:
ELISA, WB
Application Note:
Human CD3E&CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus, followed by a polyhist
Predicted Molecular Weight:
39.2 kDa (CD3E) & 38.6 kDa (CD3G)
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
CD3E
Additional Names:
CD3 epsilon & CD3 gamma,CD3E & CD3G
Protein Accession Number:
NP_000724.1 (CD3E) & AAI13831.1 (CD3G)
Ncbi Gene Id Number:
916
Background:
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Background Reference 1:
Gold DP, et al., 1986, Nature 321 (6068): 431–4.
Background Reference 2:
Clevers HC, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (21): 8156–60.
Background Reference 3:
Gil J, et al., 2011, J Clin Invest, 121(10):3872-6.
Background Reference 4:
Lu X, et al.,2011, Hematology, 16(3):185-9.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-551

List Size:
0.05 mg

List Price:

$577.00

Datasheet
Shipping Info

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